Comparing to different reaction methods, the method starting from 1,3-dimethyladamantane was certified with the memantine hydrochloride synthesized by bromination ,acetimidolation, hydrolysis and acidation.
通过比较不同的反应路线,确定了以1,3-二甲基金刚烷为原料,经溴代、乙酰氨基化、水解反应最后经酸化得到盐酸美金刚胺。
Bromacil was synthesized using 2-bromobutane and urea as the starting materials in three steps including condensation,cyclization and bromination with total yield of 61%.
以2-溴丁烷和尿素作为起始原料,经缩合、环化、溴代三步反应得到除草定,总收率为61%。
