Effect of levcromakalim on ET-1 induced proliferation and expression of protein kinase C in vascular smooth muscle cells;
拉马克啉对内皮素-1诱导的大鼠血管平滑肌细胞增殖及蛋白激酶C表达的作用
Objective: To observe the effect of Levcromakalim(Lev),an ATP-sensitive potassium channel opener,on the proliferation and apoptosis of cultured rats vascular smooth muscle cells(VSMCs) induced by endthelin-1(ET-1) in vitro.
目的:探讨ATP敏感性钾通道开放剂拉马克啉(Levcromakalim,Lev)对内皮素-1(ET-1)诱导的血管平滑肌细胞(VSMCs)增殖及凋亡的影响。
